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Development of Mammography Computer Aided Diagnosis (CAD)

-      Multiresolution local texture features for mass classification

 

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2010 . 11 ~ current

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1. Introduction

l  Computer-aided Detection (CADe) for breast cancer screening using mammography

n  To help radiologists find cancer

n  To help radiologists avoid missing cancer

l  Main limitation of current CAD systems is high false-positive (FP) detection rates

n  Unnecessary biopsies

n  Financial expense to the health care system

n  Adding unnecessary workload to radiologists/pathologists/surgeons

l  We propose a new and novel approach for the extraction of texture features for FP reduction purpose

n  Using Local Binary Pattern (LBP) operation

n  Charactering regional texture patterns of mass subregions

n  Capturing spatial structure information of mass

n  Employing multiresolution analysis

 

2. LBP texture feature extraction

2.1. LBP operation

 

 

2.2. Region-of-interest (ROI) partition

l  Objective

n  To characterize texture patterns of the masses on a regional level

n  To capture spatial structure (global geometry) of the masses

l  Rationale

n  A mass ROI is likely to be have several subregions showing different texture statistics

 

 

2.3. Extracting LBP Patterns of Core and Ribbon Regions

 

2.4. Multiresolution Analysis

l  Exploiting additional discriminant information

l  Using LBP operation for any quantization of the angular space and for any spatial resolution

 

 

 

2.5. Hierarchical Encoding Structure

 

 

 

3. Experiments

3.1. Experimental setup

l  Mammographic Image Analysis Society (MIAS) dataset

l  89 case samples/1,693 ROIs (72 mass ROIs and 1,621 normal ROIs)

l  Support Vector Machine (SVM) classifier

 

 

 

3.2. Experimental result

 

 

4. Conclusions

l  LBP texture patterns extracted from both core and ribbon regions are effective for classification of mass and normal tissues

l  Incorporating multiresolution analysis is helpful for improving the classification

l  Studies are underway with a larger and more generalized dataset collected from a large number of patients undergoing routine mammography screening

 

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      Contact Person: Prof. Yong Man Ro (ymro@kaist.ac.kr)

 

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¡°Multiresolution Local Binary Pattern texture analysis for false positive reduction in computerized detection of breast masses on mammograms,¡± Jae Young Choi, Dae Hoe Kim, Seon Hyeong Choi, and Yong Man Ro, SPIE Medical Imaging, February 2012, San Diego, California (USA)